Table 3 Kinetics of carbonylated proteins production on C. elegans after acute irradiation at 2.5 Gy (1 Gy.min−1) and at 75 Gy (15 Gy.min−1).

From: Precoce and opposite response of proteasome activity after acute or chronic exposure of C. elegans to γ-radiation

Time post irradiation (h)

Control

1 h

1h30

2 h

2h40

3 h

4 h

5 h

6 h

2.5 Gy

1 ± 0.1

1.2 ± 0.2

0.9 ± 0.1

1.6 ± 0.4

NA

2.0 ± 0.7*

NA

1.9 ± 0.7

1.3 ± 0.2

75 Gy

1 ± 0.2

1.2 ± 0.2

0.8 ± 0.2

NA

2.0 ± 0.2***

NA

1.9 ± 0.1***

2.1 ± 0.3***

NA

  1. Worms used in this assay were 3 hours synchronized, irradiated at 2.5 and 75 Gy, and collected at different times post irradiation as indicated. n = 3 (pool of 1000 nematodes). Data are expressed as induction (ratio of carbonylated protein level between exposed and controls) of carbonylated proteins compared to controls as means ± SD (*P < 0.05; **P < 0.01; ***P < 0.001, Dunnet test). NA corresponds to No Available Data.