Table 2 Differential expression of carbohydrate utilisation gene loci in B. breve UCC2003PK1 or B. breve UCC2003ΔnagA1ΔnagA2PK1 under in vivo conditions in dam-reared neonatal mice.

From: Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut

Locus tag

Function

Fold upregulation UCC2003

Fold upregulation UCC2003ΔnagA1ΔnagA2

Sialic acid metabolism

Bbr_0160

Conserved hypothetical protein

2.80a

—b

Bbr_0161

Conserved hypothetical protein in ROK family

—

—

Bbr_0162

N-acetylmannosamine-6-phosphate 2-epimerase

4.52

2.39

Bbr_0163

Hydrolase

—

—

Bbr_0164

Substrate binding protein

11.89

—

Bbr_0165

ABC transport system permease protein

5.36

—

Bbr_0166

ABC transport system ATP-binding protein

7.60

3.11

Bbr_0167

ABC transport system ATP-binding protein

7.57

—

Bbr_0168

nanA N-acetylneuraminate lyase

20.35

4.7

Bbr_0169

Glucosamine-6-phosphate isomerase

9.00

—

Bbr_0171

Sialidase A

4.49

—

Bbr_0172

ATPase

—

—

nag genes and metabolism of sulphated sugars

Bbr_0846

nagA1 N-acetylglucosamine-6-phosphate deacetylase

2.0

—

Bbr_0847

nagB2 Glucosamine-6-phosphate isomerase

3.78

—

Bbr_0851

Glucose/fructose transport protein

5.55

2.95

Bbr_0852

Sulfatase family protein

2.04

—

Bbr_0853

atsB Arylsulfatase regulator (Fe-S oxidoreductase)

—

—

Bbr_0854

Conserved hypothetical

2.12

—

Bbr_0855

Hypothetical protein

5.14

—

Lactose metabolism

Bbr_1550

Hypothetical protein

6.24

4.94

Bbr_1551

lacS Galactoside symporter

4.50

3.86

Bbr_1552

lacZ6 Beta-galactosidase

4.41

4.25

Fucose metabolism

Bbr_1741

Conserved hypothetical protein

4.91

—

Bbr_1742

L-fucose permease

3.16

—

Bbr_1743

Short chain dehydrogenase

3.35

—

Bbr_1744

Mandelate racemase

3.33

—

Bbr_1745

Transcriptional regulator

—

—

Remnants of Putative N-acetylglucosamine PTS system

Bbr_1878

Hypothetical protein

3.27

—

Bbr_1879

PTS system, glucose-specific IIABC component

6.15

—

Bbr_1880

PTS system, N-acetylglucosamine-specific IIBC component

6.77

3.78

  1. aFold upregulation ≥2 and p value ≤ 0.001. bValues below threshold.
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