Table 3 Candidate gene list for hemolysis activity by pathway-centric search.

From: Network-based genetic investigation of virulence-associated phenotypes in methicillin-resistant Staphylococcus aureus

Rank

Gene ID (New locus tag)

Pathway-Centric Search Score

Mutant Strain Availability (Tested Rank)

Significant Change in Hemolysis Ability

1

SAUSA300_RS11335

24.58

TRUE (1)

FALSE

2

SAUSA300_RS05175

22.24

TRUE (2)

FALSE

3

SAUSA300_RS07105

22.04

TRUE (3)

FALSE

4

SAUSA300_RS11410

20.84

FALSE

Not tested

5

SAUSA300_RS11425

20.64

TRUE (4)

FALSE

6

SAUSA300_RS07100

19.34

TRUE (5)

FALSE

7

SAUSA300_RS11990

18.85

FALSE

Not tested

8

SAUSA300_RS01250

18.38

TRUE (6)

FALSE

9

SAUSA300_RS11355

18.36

TRUE (7)

FALSE

10

SAUSA300_RS02850

18.23

FALSE

Not tested

11

SAUSA300_RS07405

17.96

TRUE (8)

FALSE

12

SAUSA300_RS07430

17.58

FALSE

Not tested

13

SAUSA300_RS12145

17.27

FALSE

Not tested

14

SAUSA300_RS11400

17.06

FALSE

Not tested

15

SAUSA300_RS11380

16.85

TRUE (9)

FALSE

16

SAUSA300_RS02805

16.66

FALSE

Not tested

17

SAUSA300_RS09090

16.66

FALSE

Not tested

18

SAUSA300_RS06220

16.59

FALSE

Not tested

19

SAUSA300_RS06165

16.02

TRUE (10)

Gamma type hemolysis, Quantitative assay p < 0.01