Figure 3
(A) The pair-distance distribution function, P(r) for the dysferlin FerA four-helix bundle. The P(r) calculated from GNOM (∙) and the best-fit CORAL model’s theoretical P(r) (red-line) are shown for comparison. (B) SAXS-constrained FerA ab initio and rigid-body models. The superpositioned GASBOR ab initio bead model and a Robetta based CORAL model in perpendicular side views. The CORAL model’s missing N-terminal residues were modeled as a flexible C α chain. The polypeptide chain progresses along a rainbow of color from a blue N-terminus to a red C-terminus. The additional N-terminal residues from the cloning vector are included.
