Table 1 Research and design of osteoporosis animals.

From: Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis

Group

Test article

Route

No. of Rats

Dose level

Dosing frequency

Sham

Vehicle

p.o.

12

1 ml/kg

Once per 3 days

Vehicle control

Vehicle

p.o.

13

1 ml/kg

Once per 3 days

Treatment-

NC-8-1 mg/kg

NC-8

p.o.

12

1 mg/kg

Once per 3 days

Treatment-

NC-8-3 mg/kg

NC-8

p.o.

12

3 mg/kg

Once per 3 days

Treatment-

NC-8-10 mg/kg

NC-8

p.o.

12

10 mg/kg

Once per 3 days

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