Table 2 Mean volume change of selected structures in % with corresponding sample sizes for different clinical groups. Standard deviation in parentheses.
bl → m12 | hippocampus | inf. lat. vent. | lat. vent. | med. temp. gyr. | brain tissue | ventricles | white matter | cort. GM | deep GM | |
|---|---|---|---|---|---|---|---|---|---|---|
Atrophy rates | HC | −1.1 (1.7) | 1.8 (3.3) | 3.0 (3.2) | −1.1 (1.5) | −0.5 (0.8) | 2.8 (3.0) | −0.2 (0.7) | −0.8 (1.4) | −0.8 (1.3) |
sMCI | −1.7 (2.2) | 2.6 (3.8) | 3.6 (3.3) | −1.4 (1.8) | −0.6 (0.8) | 3.4 (3.1) | −0.4 (0.7) | −0.8 (1.3) | −0.7 (1.3) | |
pMCI | −4.1 (3.2) | 6.7 (5.6) | 7.1 (4.6) | −3.1 (2.4) | −1.2 (1.0) | 6.8 (4.3) | −0.6 (0.9) | −1.8 (1.7) | −1.3 (1.2) | |
AD | −4.8 (3.7) | 7.5 (5.5) | 7.6 (4.9) | −3.8 (2.7) | −1.3 (1.1) | 7.2 (4.6) | −0.8 (1.0) | −1.9 (2.3) | −1.4 (1.6) | |
Sample sizes | sMCI (uncor.) | 412 | 548 | 217 | 384 | 383 | 215 | 966 | 674 | 739 |
sMCI (HC-cor.) | 3130 | 5190 | 7499 | 8823 | 17269 | 6337 | 2834 | 18432936 | 1429741 | |
pMCI (uncor.) | 155 | 175 | 104 | 143 | 168 | 100 | 488 | 235 | 218 | |
pMCI (HC-cor.) | 284 | 321 | 309 | 351 | 535 | 285 | 864 | 813 | 1349 | |
AD (uncor.) | 148 | 134 | 104 | 133 | 182 | 101 | 413 | 366 | 336 | |
AD (HC-cor.) | 244 | 228 | 285 | 270 | 493 | 265 | 640 | 640 | 1133 | |
bl → m24 | hippocampus | inf. lat. vent. | lat. vent. | med. temp. gyr. | brain tissue | ventricles | white matter | cort. GM | deep GM | |
Atrophy rates | HC | −2.0 (2.3) | 3.5 (4.5) | 6.3 (4.0) | −2 (1.6) | −1.1 (0.8) | 5.8 (3.7) | −0.6 (0.8) | −1.6 (1.7) | −1.3 (1.3) |
sMCI | −3.7 (3.8) | 6.2 (6.5) | 7.5 (6.0) | −2.6 (2.6) | −1.2 (1.0) | 7.1 (5.6) | −0.8 (1.0) | −1.7 (1.5) | −1.2 (1.0) | |
pMCI | −8.9 (5.1) | 14.6 (8.9) | 14.4 (7.9) | −6.1 (3.9) | −2.3 (1.5) | 13.7 (7.4) | −1.6 (1.3) | −3.2 (2.5) | −2.1 (1.4) | |
AD | −10.2 (6.2) | 15.9 (8.8) | 15.4 (8.5) | −6.8 (4.1) | −2.6 (1.3) | 14.7 (7.8) | −1.8 (1.4) | −3.5 (2.4) | −2.3 (1.8) | |
Sample sizes | sMCI (uncor.) | 264 | 274 | 158 | 246 | 173 | 158 | 370 | 215 | 176 |
sMCI (HC-cor.) | 1166 | 1446 | 6179 | 4588 | 23154 | 5166 | 4764 | 102542 | 23243 | |
pMCI (uncor.) | 82 | 92 | 76 | 105 | 99 | 73 | 163 | 155 | 107 | |
pMCI (HC-cor.) | 136 | 160 | 241 | 233 | 372 | 220 | 412 | 618 | 782 | |
AD (uncor.) | 93 | 76 | 75 | 92 | 67 | 71 | 145 | 123 | 162 | |
AD (HC-cor.) | 142 | 126 | 217 | 185 | 216 | 195 | 316 | 420 | 980 | |
