Table 5 Overview over selected articles that use features from T1w MR images from the ADNI cohort. Table adapted from Falahati et al.7. CTH: cortical thickness, ENR: elastic net regression, HV: hippocampus, LLE: locally linear embedding, MBL: manifold-based learning, MIL: multiple instance learning, OPLS: orthogonal partial least square to latent structure, SR: spare regression, TBM: tensor-based morphometry.
Article | Dataset (field strength) | Features | Classifier | AD vs. HC | pMCI vs. sMCI | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
bACC | SENS | SPEC | NAD/NHC | bACC | SENS | SPEC | NpMCI/NsMCI | ||||
MALPEM | ADNI1/Go/2 (1.5/3 T) | ROI volumes | RF | 86 | 83 | 90 | 322/404 | 68 | 72 | 64 | 177/166 |
MALPEM | ADNI1/Go/2 (1.5/3 T) | ROI volumes | SVM | 89 | 86 | 92 | 322/404 | 67 | 70 | 64 | 177/166 |
Beheshti et al.82 | ADNI1 (3T) | VBM+ROM and intensity features | SVM | 93 | 89.1 | 96.8 | 92/94 | 75 | 76.9 | 73.2 | 71/65 |
Coupe et al.28 | ADNI1 (1.5T) | ROI volumes and grading features | LDA | 90.5 | 87 | 94 | 198/231 | 73.5 | 73 | 74 | 167/238 |
Chincarini et al.63 | ADNI1 (1.5T) | intensity and textural features features from 9 ROIs | SVM | 91.5 | 89 | 94 | 144/189 | 68.5 | 72 | 65 | 136/166 |
Guerr`ero et al.49 | ADNI1 (1.5T) | learned ROIs via SR + MBL | SVM | 85.5 | 86 | 85 | 106/175 | 71 | 75 | 67 | 116/114 |
Hu et al.83 | ADNI1 (1.5T) | VBM and wavelet frame features | SVM | 84.1 | 82.5 | 85.6 | 288/188 | 76.7 | 71.8 | 82.3 | 71/62 |
Liu et al.61 | ADNI1 (1.5T) | ROI volumes, CTH | ENR + LLE | 89.5 | 86 | 93 | 86/137 | 68 | 80 | 56 | 97/93 |
Tong et al.50 | ADNI1 (1.5T) | local intensity patches | MIL | 89 | 85 | 93 | 198/231 | 70 | 67 | 73 | 167/238 |
Wee et al.60 | ADNI1 (1.5T) | correlative and ROI-based morphological features | SVM | 92.4 | 90.4 | 94.3 | 198/200 | 74.0 | 63.5 | 84.4 | 89/111 |
Westman et al.62 | ADNI1 (1.5T) | ROI volumes, CTH, curvature and folding features | OPLS | 91.5 | 90 | 93 | 187/225 | 71.2 | 75.9 | 66.5 | 87/200 |
Wolz et al.34 | ADNI1 (1.5T) | HV, CTH, TBM, MBL | LDA | 89 | 93 | 85 | 198/231 | 68 | 67 | 69 | 167/238 |
Zu et al.84 | ADNI1 (1.5T+PET) | ROI volumes | SVM | 96 | 95.1 | 94.5 | 51/52 | 69.8 | 66.7 | 71.4 | 56/43 |