Table 3 Multivariate analysis of the effect of telomere length and composite genetic risk score on melanoma-specific survival.

From: Telomere length and survival in primary cutaneous melanoma patients

 

Composite genetic risk score/Telomere length*

N

Dead

HR (95% CI)Ɨ

P

Telomere length

Low risk + long telomeres

208

8

ref

 

Low risk + short telomeres

239

24

1.74 (0.78–3.99)

0.17

High risk + long telomeres

197

17

2.41 (1.04–5.61)

0.04

High risk + short telomeres

213

27

2.19 (0.97–4.91)

0.06

  1. *The composite genetic risk score was dichotomized at median distribution (low risk ≤ 0 and high risk > 0). The telomere length was dichotomized at median distribution of T/S ratios (long > 1.20 and short ≤ 1.20).
  2. ƗHazard ratio (HR) was adjusted for age at diagnosis, gender, number of nevi, tumor location and tumor stage.
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