Table 4 Multivariate analysis of effect of telomere length on melanoma-specific survival in age-matched groups.

From: Telomere length and survival in primary cutaneous melanoma patients

  

N

Dead

HR (95% CI)

P

Telomere length

Long (T/S ratio > 1.20)

290

18

ref

 

Short (T/S ratio ≤ 1.20)

308

36

1.79 (1.01–3.17)

0.05

Composite genetic risk score

(continuous)

598

54

2.89 (1.26–6.59)

0.01

Sex

Males

254

33

ref

 

Females

344

21

0.49 (0.27–0.87)

0.02

Tumor location

Axial

326

34

ref

 

Extremities

228

12

0.60 (0.30–1.19)

0.14

Acral/Mucosal

44

8

2.34 (1.03–5.31)

0.04

Tumor stage*

1 (1A, 1B)

436

22

ref

 

2 (2A, 2B, 2C)

162

32

3.60 (2.05–6.30)

<0.0001

  1. *As tumor stage is defined by Breslow thickness, presence/absence of ulceration and tumor mitotic rate, therefore only tumor stage was included in the analysis.
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