Figure 5 | Scientific Reports

Figure 5

From: Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium

Figure 5

Transcriptional meta-signature associated with ZIKV infection. (A) Gene ontology clusters associated with ZIKV meta-signature. Dysregulated genes of multiple biological processes related to defense response against viruses and the type I interferon response. (B) Pathways are significantly dysregulated by ZIKV infection in multiple cell types. The significance of effect on pathways was estimated by one-tailed Fisher exact test. (C) Key transcriptional regulators significantly activated in ZIKV meta-signature.

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