Figure 8 | Scientific Reports

Figure 8

From: Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium

Figure 8

Comparative analysis of ZIKV and DENV in modulating meta-analysis-predicted genes in RPE cells. Human primary RPE cells were challenged with ZIKV or DENV, type 2, at MOI of 1 for the indicated time points; uninfected cells served as control. (A) DENV-infected cells were immunostained for anti-flavivirus group antigen 4G2 (image magnification 20X). (B) Expression of key regulator genes was assessed by qRT-PCR. Graphs show the statistical analyses of relative mRNA levels after normalization using β-actin. Results are expressed as mean ± S.D. of three independent experiments, *P < 0.05, **P < 0.005.

Back to article page