Figure 8
From: Cyclooxygenase-2 up-regulates hepatic somatostatin receptor 2 expression
Schematic of mechanism by which COX-2 regulates SSTR-2 expression. COX-2 up-regulate SSTR-2 expression in the cirrhotic liver. The presumable mechanism is that CREB may participate in this regulatory process via the PKC signaling pathway, while DNA methylation and the p38 signaling pathway are not likely involved in this process.
