Table 1 Clinical Characteristics of Septic Patients for Derivation Cohort & Validation Cohort.

From: Challenges and Opportunities for Emergency Department Sepsis Screening at Triage

 

Parameter

Derivation Cohort Septic Patients (12-mo interval)

Validation Cohort Septic Patients (3-mo interval)

(n = 141)

(n = 50)

Triage

Age, yrs, median (IQR)

70 (58–81)

65 (53–75)

Febrile (Temp > 100.4 °F)

29 (21%)

5 (10%)

Heart Rate, bpm, median (IQR)

104 (84–120)

97 (78–118)

Systolic Blood Pressure, mmHg, median (IQR)

100 (76–120)

106 (87–135)

Triage SBP < 100

70 (50%)

20 (40%)

Triaged to Non-Acute ED Area

25 (18%)

3 (6%)

tCFI: triage Concern for Infection

In all patients:

n = 141

n = 50

tCFI: Probable

46 (33%)

21 (42%)

Possible

95 (67%)

28 (56%)

Unlikely

0

1 (2%)

In patients with a Sepsis Risk Factor:

135 (96%)

44 (88%)

tCFI: Probable

42 (30%)

19 (38%)

Possible

93 (66%)

24 (48%)

Unlikely

0

1 (2%)

Clinical Details

Documented SBP < 90 in ED

135 (96%)

47 (94%)

Time from Triage to SBP < 90, hours, median (IQR)

0.7 (0.0–2.5)

0.7 (0.1–2.1)

Total IV Fluids, L, median (IQR)

3.00 (2.00–4.00)

2.65 (1.55–3.98)

Serum Lactate, mmol/L, median (IQR)

2.7 (1.7–3.9)

2.6 (1.9–3.8)

SOFA Score, median (IQR)

9 (7–11)

9 (7–12)

Hospital Mortality

38 (27%)

15 (30%)

SPoT Vitals

Met SPoT Vital-Signs Criterion in the ED

141 (100%)

50 (100%)

Time from Triage to SPoT, hours, median (IQR)

0.0 (0.0–0.4)

0.1 (0.0–0.8)

qSOFA Vitals

Met qSOFA Vital-Signs Criterion in the ED

127 (90%)

43 (86%)

Time from Triage to qSOFAa, hours, median (IQR)

0.6 (0.1–1.8)

0.7 (0.1–1.4)

  1. aExcludes patients who never met qSOFA vital-signs criterion in ED.