Figure 3
From: Allosteric sodium binding cavity in GPR3: a novel player in modulation of Aβ production
Expression and subcellular localization of WT GPR3 and mutants. Representative confocal images of HEK 293 (A) and H4swe (B) cells expressing wild-type (WT) or single point mutants of GPR3. Cells were fixed with 4% paraformaldehyde 24 hours post transfection and stained with a monoclonal antibody against the Myc epitope fused to the C-terminal end of the receptor. The nuclei were stained with DAPI (blue). Single Z-planes (right panels) and maximum intensity projections (Z-stack, left panels) are shown for each sample.
