Figure 2

Dose-effect relationships for myocardial uptake of 11C-HED. (A) Retention index. The estimated retention indices as a marker of norepinephrine re-uptake function decreased at lower specific activity (i.e. higher amount of cold mass). (B) Washout Rate. The washout rate increased as loaded cold mass increased. Every dot represents one investigated animal, dotted lines show 95% inclusion limits and solid lines indicate dose-effect curves.