Table 2 Kinetic parameters of mutants NaCTp.L485R and NaCTp.F500L.

From: Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism

 

Km [µM]

Vmax [pmol × mg protein−1 × min−1]

NaCT-wild-type

1 439 ± 270.8

13 910 ± 903.2

NaCTp.L485R

4 611 ± 1 849

17 333 ± 3 664

NaCTp.F500L

655.4 ± 370.0

9 335 ± 1 375

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