Table 4 Genes associated with biofilm production and their functions/putative functions.

From: Metagenomics of pigmented and cholesterol gallstones: the putative role of bacteria

EPS related genes

Function of gene products/putative function

Reference(s)

Gram-negative bacteria

Klebsiella

   CsgD

Transcriptional regulator

39

   Gsp

General stress protein 18

38

   fim Type I

Type 1 fimbriae fimA,B,D,E,L,F,G

12,39

   fim Type IV

Type IV fimbrial assembly, ATPase PilB

12,39

   wza

Polysaccharide export lipoprotein

12,39

   wzc

Tyrosine-protein kinase

12,39

   Ribose ABC Transport System

Ribose ABC transport system, ATP-binding protein RbsA

39

   Ribose ABC Transport System

Ribose ABC transport system, permease protein RbsC

39

   Autoinducer 2(AI-2)

ABC transport system, fused AI2 transporter subunits and ATP-binding component

39

   CP4-57- integrase

putative CP4-57-type integrase

39

   Polyphosphate kinase

Polyphosphate kinase- Biofilm development

48

   sugE

Quaternary ammonium compound-resistance protein

12

   ClpX

ATP-dependent Clp protease ATP-binding subunit

12

   RapA

RNA polymerase associated protein reg. yhcQ, YeeZ

17

   LuxR

Transcriptional regulator

12

   CspD

Cold shock protein CspD

12

Escherichia

   wzb

Low molecular weight protein-tyrosine-phosphatase

39

   wzc

Tyrosine-protein kinase

39

Gram-positive bacteria

Enterococcus

   RbsA

Ribose ABC transport system, ATP-binding protein

39

   galE

UDP-glucose 4-epimerase

41

   sugE

Quaternary ammonium compound-resistance protein SugE

12

   ClpX

ATP-dependent Clp protease ATP-binding subunit

12

   LuxR

Transcriptional regulator

12

   CspD

Cold shock protein CspD

12