Table 1 Characteristics of subjects.
RNA-seq group | Replication group (qPCR) | Replication group (immunohistochemistry) | Serum biomarker group | |
---|---|---|---|---|
Characteristics | ||||
Subject no. | 6 | 14 | 110 | 369 |
Gender (M/F) | 4/2 | 12/2 | 68/42 | 239/130 |
Age (mean ± SD) | 56.7 ± 15.0 | 57.4 ± 18.3 | 56.1 ± 14.7 | 53.7 ± 14.6 |
Comorbid of asthma | 2/6 (33.3%) | 3/14 (21.4%) | 31/110 (28.2%) | 124/369 (33.6%) |
Diagnosis | ||||
Non-ECRS | 2 | 6 | 34 | 122 |
Mild ECRS | 0 | 2 | 20 | 64 |
Moderate ECRS | 3 | 4 | 35 | 116 |
Severe ECRS | 1 | 2 | 21 | 67 |
Experiments | ||||
RNA-seq | 6 | (−) | (−) | (−) |
qPCR | 6 | 14 | (−) | (−) |
Immunohistochemistry | 6 | (−) | 110 | (−) |
ELISA (periostin) | (−) | (−) | (−) | 369 |