Figure 4
From: Endoscopic Transplantation of Mesenchymal Stem Cell Sheets in Experimental Colitis in Rats
Evaluation of MSC sheet endoscopic transplantation in electrocoagulation model. (a) Endoscopic imaging of the colon induced by electrocoagulation ulcer (left). and MSC sheets transplanted at the site of induction of electrocoagulation ulcer (middle). The yellow arrow points to the transplantation site. One day after MSC sheets endoscopic transplantation (right). (b) Macroscopic representation of the ulcer formation on colon in 1 day after MSC sheets endoscopic transplantation. The yellow arrow points to the transplanted ulcer site. (c) Histological analysis of colon tissue 0 day after MSC sheets. (d) Histological analysis of colon tissue 1 day after MSC sheets (middle; AD-MSC, lower; BM-MSC) transplantation group. Con; only electrocoagulation, Sham; transplanted without MSC sheets, AD-MSC; AD-MSC sheets transplanted, BM-MSC; BM-MSC sheets transplanted. The red fluorescent signal is an EGFP signal in immunofluorescence, Dark brown stain was EGFP signal in DAB stain. GFP/E-Cad/DAPI; immunofluorescence stain, Brown GFP; immunohistochemistry, HE; Hematoxylin and eosin stain. Bars represent 200 μm.
