Figure 8
From: Magnetite-Gold nanohybrids as ideal all-in-one platforms for theranostics

Fe3O4-Au Janus NPs as MRI contrast agents. (a) Proton T2 relaxation time as a function of iron concentration for NP-PEG in water and in 4T1 cells. The R2 value is determined by the slope of the linear fitting. (b) T2-weighted images of NPs serial dilutions acquired at TE = 24 ms in water (top panel) and 4T1 cells (bottom panel). (c) Representative T2-weighted images of BALB/c mouse with both flanks grafted 4T1 tumors captured before and within 24 h after NPs (6.6 mg·kg−1 Fe3O4) i.v. injection (see also Supplementary Figure S12). Areas with enhanced tumor contrasting are indicated by arrows.