Table 1 Clinical and biological parameters of patients among the three groups.

From: Differential expression of serum biomarkers in hemodialysis patients with mild cognitive decline: A prospective single-center cohort study

Variable

HC (n = 20)

NCF (n = 29)

MCD (n = 29)

F

t

χ2

P

Male [n (%)]

11 (55.00)

15 (51.70)

15 (51.70)

  

0.11

0.97

Age (years)

45.00 ± 8.90

43.10 ± 7.80

48.00 ± 7.20

2.87

  

0.06

Education (years)

11.10 ± 3.06

11.24 ± 2.46

10.83 ± 2.25

0.19

  

0.82

Type of kidney diseases

     

9.88

0.27

Chronic glomerulonephritis

17

15

    

Diabetic nephropathy

1

5

    

Benign arteriolar nephrosclerosis

0

1

    

Polycystic kidney

1

1

    

IgA nephropathy;

0

1

    

Medullary sponge kidney

0

1

    

Chronic kidney disease of unknown etiology

6

5

    

Nephrotic syndrome

3

0

    

Systemic lupus erythematosus nephropathy

1

0

    

HB (g/L)

142.20 ± 20.20

107.90 ± 13.00

108.90 ± 12.80

37.23

  

<0.001***

HCT (L/L)

0.43 ± 0.05

0.33 ± 0.04

0.33 ± 0.04

38.54

  

<0.001***

WBC (10 9/L )

6.14 ± 1.26

5.99 ± 1.80

5.79 ± 1.61

0.29

  

0.75

RBC (10 12/L )

4.94 ± 0.45

3.69 ± 0.50

3.69 ± 0.52

47.15

  

<0.001***

BUN (mmol/L)

4.40 ± 0.85

27.55 ± 5.71

24.33 ± 4.42

179.30

  

<0.001***

Cr (umol/L)

71.55 ± 8.65

1052.00 ± 195.90

965.00 ± 172.50

258.40

  

<0.001***

ALB (g/L)

46.04 ± 2.49

40.04 ± 1.99

41.46 ± 4.03

24.40

  

<0.001***

Dialysis duration (months)

71.52 ± 38.13

78.07 ± 47.39

 

0.58

 

0.56

Calcium (mmol/L)

2.15 ± 0.24

2.25 ± 0.29

 

1.34

 

0.18

Phosphate (mmol/L)

2.25 ± 0.70

2.07 ± 0.69

 

0.96

 

0.33

PTH (pg/mL)

534.3 ± 478.2

420.5 ± 362.6

 

1.02

 

0.31

Dry weight (kg)

61.42 ± 11.25

58.00 ± 8.28

 

1.32

 

0.19

  1. Data are shown as means ± standard error of means (n = 20–29), ***p < 0.001. ALB: albumin; BUN: blood urea nitrogen; Cr: creatinine; HB: haemoglobin; HC: healthy control group; HCT: haematocrit; MCD: mild cognitive decline group; NCF: normal cognitive function group; PLT: blood platelet; PTH: parathyroid hormone RBC: red blood cell; WBC: white blood cell.