Figure 1 | Scientific Reports

Figure 1

From: Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer’s disease

Figure 1

Pathology in the AD-STG. (A) (i–ii) Photomicrographs of Garvey silver staining from the STG of (i) a control showing no pathology and (ii) an AD case with numerous plaques and a single intracellular NFT (indicated by →). Scale bar in main images represents 20 μm. Scale bar to the insets represents 40 μm. (iii–iv) Photomicrographs of AT8 immunostaining from the STG of (iii) a control and (iv) an AD case with numerous tau-positive neurons including an intracellular NFT (indicated by →). CP = cored plaque; DP = diffuse plaque; IT = intracellular neurofibrillary tangle. (B) AT8 (tau) immunoblotting of whole brain homogenates showing hyperphosphorylated tau (positive bands in the range 45–79 kDa) in the AD samples (for complete image refer to Supplementary Fig. S1).

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