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Figure 1

From: oxLDL inhibits differentiation and functional activity of osteoclasts via scavenger receptor-A mediated autophagy and cathepsin K secretion

Figure 1

oxLDL inhibits fusion of mononuclear cells. Monocytes plated on glass coverslips were grown in the presence of M-CSF and RANKL for a total of 15 days, and then TRAP staining was carried out. (A) TRAP staining of control and oxLDL treated cells. (B) Quantification of the average number of TRAP positive cells. (C) Average number of nuclei per TRAP positive cell. (D) Quantification of the average size of TRAP positive cell. Magnification x25, scale bar 200 µm. n ≥ 3 (E) mRNA expression of CalcR with and without oxLDL.

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