Figure 6
From: Histone deacetylase inhibitor, CG200745 attenuates renal fibrosis in obstructive kidney disease
Effects of CG200745 on epithelial-mesenchymal transition and fibrosis in TGF-β treated HK-2 cell. HK-2 cells were exposed to TGF-β (2 ng/ml, 16 h) with or without treatment with CG200745 (10 μM). (A) Protein expression of the α-SMA and fibronectin were analyzed. (B) Protein expression of the Smad2/3 and Smad4 were analyzed. Each column represents mean ± SEM. *p < 0.05, compared with the control. #p < 0.05, compared with TGF-β treated HK-2 cells.
