Table 3 Associations between various glucose parameters and clinical outcomes.

From: Clinical Implications of Serial Glucose Measurements in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis

 

mRS 0–2 at 3 months

Unadjusted OR (95% CI)

P-value

Adjusted OR (95% CI)

P-value

Initial BG

   for every 30-mg/dl increase

0.98 (0.88–1.09)

0.72

1.01 (0.90–1.14)

0.87

   1Q

Ref

 

Ref

 

   2Q

0.72 (0.44–1.19)

0.20

0.80 (0.45–1.42)

0.44

   3Q

0.76 (0.46–1.27)

0.30

0.77 (0.44–1.38)

0.38

   4Q

0.70 (0.42–1.17)

0.18

0.75 (0.42–1.33)

0.33

Mean BG

   for every 30-mg/dl increase

0.79 (0.66–0.95)

0.01

0.82 (0.67–1.01)

0.06

   1Q

Ref

 

Ref

 

   2Q

0.76 (0.46–1.25)

0.28

0.81 (0.46–1.44)

0.48

   3Q

0.55 (0.33–0.91)

0.02

0.57 (0.32–1.01)

0.05

   4Q

0.41 (0.25–0.70)

<0.001

0.44 (0.24–0.81)

0.01

Max BG

   for every 30-mg/dl increase

1.00 (0.91–1.10)

0.95

1.01 (0.91–1.13)

0.85

   1Q

Ref

 

Ref

 

   2Q

1.03 (0.62–1.71)

0.90

1.30 (0.73–2.31)

0.37

   3Q

0.59 (0.35–0.99)

0.04

0.62 (0.34–1.11)

0.10

   4Q

0.95 (0.57–1.57)

0.84

0.99 (0.56–1.77)

0.98

SD

   for every 10-unit increase

1.11 (1.00–1.23)

0.04

1.11 (0.99–1.25)

0.08

   1Q

Ref

 

Ref

 

   2Q

0.95 (0.57–1.58)

0.83

1.04 (0.58–1.86)

0.89

   3Q

0.98 (0.59–1.65)

0.95

1.08 (0.61–1.92)

0.80

   4Q

1.46 (0.88–2.42)

0.14

1.40 (0.80–2.47)

0.24

CoV

   for every 10% increase

1.40 (1.16–1.68)

<0.001

1.38 (1.12–1.71)

0.003

   1Q

Ref

 

Ref

 

   2Q

0.76 (0.45–1.27)

0.29

0. 802 (0.44–1.43)

0.49

   3Q

1.20 (0.73–1.98)

0.48

1.27 (0.73–2.23)

0.40

   4Q

1.93 (1.15–3.24)

0.01

1.91 (1.07–3.43)

0.03

J index

   for every 10-unit increase

0.96 (0.88–1.06)

0.45

0.97 (0.88–1.08)

0.63

   1Q

Ref

 

Ref

 

   2Q

0.82 (0.50–1.36)

0.44

0.83 (0.47–1.47)

0.52

   3Q

0.67 (0.40–1.11)

0.12

0.75 (0.42–1.35)

0.34

   4Q

0.72 (0.43–1.19)

0.20

0.76 (0.42–1.37)

0.36

  1. BGs, OR for every 30-mg/dl increase in BG; SD and J index, OR for every 10-unit increase; CoV, OR for every 10% increase.
  2. Adjusted variables: age, male, initial NIHSS score, TOAST classification, endovascular therapy, AF, prior stroke, large artery occlusion, SBP, and recanalization status.
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