Table 2 Comparison of molecular characterisation of ST-4821 complex by serogroup*.

From: Invasive meningococcal disease in Shanghai, China from 1950 to 2016: implications for serogroup B vaccine implementation

Clonal complex

Sequence type

fHbp VR

NHBA VR

PorA VR

PorB VR

FetA VR

MenB:cc4821 (n = 40)

ST-5664 (9), ST-5798 (6), ST-3200 (6)

16 (23)

669 (13), 910 (8)

P1.20,23-x (26)

3-229 (12), 3-81 (8), 3-460 (5), 3-48 (4)

F1-91 (12), F3-9 (6), F5-2 (5)

MenC:cc4821 (n = 32)

ST-4821 (23)

80 (9), 22 (6), 404 (5), 419 (5)

503 (23)

P1.7-2,14 (15), P1.20,23-x (8)

3-48 (22)

F3-3 (23)

  1. *All cc4821 isolates without nadA gene.
  2. P1.20,23-x, refers to the following nine PorA variants found in this complex: P1.20-3,23, P1.20-3,23-1, P1.20-3,23-2, P1.20-3,23-3, P1.20-3,23-6, P1.20-3,23-7, P1.20-3,23-9, P1.20-3,23-19, and P1.20-3,23-28.
Back to article page