Figure 3 | Scientific Reports

Figure 3

From: Hookworm exposure decreases human papillomavirus uptake and cervical cancer cell migration through systemic regulation of epithelial-mesenchymal transition marker expression

Figure 3

Exposure to N. brasiliensis decreases the expression of murine genital tract EMT markers. (A) Western blot analysis of N-cadherin, vimentin and p38 (loading control) within the female genital tract was performed 9 days following N. brasiliensis infection or in naïve BALB/c mice (B). Densitometry readings were obtained using ImageJ in order to determine the changes in protein expression of N-cadherin and vimentin as a ratio to p38 expression. The data shown is result of (B and C). Two independent experiments or (A). Representative of two independent experiments with n ≥ 4 mice per group. The data was analysed using GraphPad Prism 6.01 and a parametric unpaired t-test was performed where ns = not significant, *p < 0.05 **p < 0.01 and ***p < 0.001. Error bars represent Standard Error of the Mean.

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