Table 2 Summary of the fetal offspring obtained through Exp-1 and -2.
Experiment | No. pregnant rats/no. rats treated | No. fetuses obtained | No. fetuses carrying de-pigmented eyes (%) | Fetuses with modified alleles | ||
---|---|---|---|---|---|---|
No. homozygous or compound heterozygous bi-allelic mutation (%) | No. heterozygous bi-allelic mutation (%) | No. mosaic mutation (%) | ||||
Exp-1 (mating between female BN and male SD) | 3/5 | 13 | 8 (62) | 2 (25) | 6 (75) | 0 (0) |
Exp-2 (mating between female SD and male BN) | 3/3 | 16 | 9 (56) | 1 (11) | 5 (56) | 3 (33) |