Figure 3
From: Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat
The minimal network used for estimating flux measurements in the tracer dilution study. Abbreviations shown are names of enzymes for which absolute flux was calculated based on metabolic flux analysis. ALDO: Aldolase; CS: Citrate synthase; ENO: Enolase; GADPH: Glyceraldehyde-3-phosphate dehydrogenase; GK: Glycerol kinase; GPI: D-glucose-6-phosphate isomerase; G6PC: D-Glucose-6-phosphatase; IDH: Isocitrate dehydrogenase; LDH: Lactate dehydrogenase; OGDH: Oxoglutarate dehydrogenase; PC: Pyruvate:carbon-dioxide ligase (ADP-forming); PCC: Propionyl-CoA carboxylase; PCK: Phosphoenolpyruvate carboxykinase; PK: GTP:pyruvate 2-O-phosphotransferase; PYGL: glycogen phosphorylase; SDH: Succinate dehydrogenase.
