Table 1 Number of differentially expressed genes (DEGs) 5 or 10 h after exposure to APAP (2 g/kg) and number of genes mapped to the iRno model.

From: Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat

Time (h)

Total number of genes

DEGs FDR < 0.10

Genes mapped to iRno

Mapped DEGs FDR < 0.10

5

11,721

1,384

1,710

241

10

11,659

2,551

1,701

512

  1. FDR: false discovery rate.