Figure 2
From: Mitochondrial DNA m.3243A > G heteroplasmy affects multiple aging phenotypes and risk of mortality

Mitochondrial m.3243A > G association with all-cause mortality. Survival was compared across tertiles of m.3243A > G heteroplasmy with a total of 263 participants included in each tertile. A significantly increased risk of all-cause mortality was observed for participants in the highest tertile of heteroplasmy when compared with those in the lowest tertile (Hazard Ratio [HR] = 1.25, 95% confidence interval [CI] = 1.01–1.56, p = 0.046). Analyses adjusted for age, sex, race, and clinic site.