Table 2 Phenotype values among tertiles of m.3243A > G heteroplasmy, mean and standard error (SE).
From: Mitochondrial DNA m.3243A > G heteroplasmy affects multiple aging phenotypes and risk of mortality
m.3243A > G heteroplasmy | 0–4% | 4–6% | 6–19% | Linear p-value |
---|---|---|---|---|
Mean (SE) | Mean (SE) | Mean (SE) | ||
Digit Symbol Substitution Test Score | 35.3 (0.73) | 33.1 (0.73) | 33.1 (0.73) | 0.04 |
Fasting insulin (uIU/mL) | 7.65 (0.55) | 8.30 (0.55) | 9.80 (0.55) | 0.04 |
Pulse wave velociy (cm/sec) | 890 (27.8) | 928 (28.3) | 976 (28.6) | 0.008 |
Grip Strength (kg) | 31.8 (0.43) | 30.9 (0.43) | 30.4 (0.43) | 0.02 |
Modified Mini-Mental State Examination Score | 91.5 (0.3) | 90.8 (0.3) | 90.9 (0.3) | 0.49 |
400 m walk speed (m/s) | 1.24 (0.013) | 1.25 (0.013) | 1.23 (0.013) | 0.94 |
Systolic blood pressure (mm Mercury) | 137.2 (1.3) | 136 (1.3) | 136.2 (1.3) | 0.30 |
Resting heart rate (beats/min) | 68.2 (0.67) | 67.5 (0.67) | 67.3 (0.66) | 0.13 |
Fasting glucose (uIU/mL) | 101.7 (1.89) | 105.5 (1.9) | 104.7 (1.9) | 0.90 |