Figure 4 | Scientific Reports

Figure 4

From: CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells

Figure 4

CEACAM1 expression in melanoma is inversely correlated with patient survival. (A) Kaplan-Meier overall-survival analysis (OS): CEACAM1 expression in melanoma samples was visualized by CEACAM1 specific immunohistochemistry in melanoma samples from 113 patients. Patients were grouped as CEACM1 “no/low” staining or CEACAM1 “medium/high” staining. CEACAM “no/low” patients show a significantly longer overall survival than CEACAM “medium/high” patients (p < 0.001). (B) A melanoma with high CEACAM1 expression: Immunohistochemical staining of paraffin embedded patient tissue for CEACAM1. (C) A CEACAM1 negative melanoma: Immunohistochemical staining of paraffin embedded patient tissue for CEACAM1.

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