Figure 7
From: Tight Junction barriers in human hair follicles – role of claudin-1

Quantification of Cldn-1 and Cldn-4 in human HFs. Immunohistochemical stainings of Cldn-1 (green; a–d) in the epithelium around the club hair (a), the epithelial strand (ES) (a,b,c) of club HF, and in the bulb of an anagen HF (d). Scale bar: 20 µm. (e) Quantitative analysis of Cldn-1 intensity in ORS of anagen bulb and epithelial strand during catagen (mean of 23 ROIs ± SEM, n = 3 different donors); (f) Cldn-1 and Cldn-4 staining intensity in human anagen HFs of healthy and AD non-lesional and lesional skin; means ± SEM of 10 ROIs per image. Statistical test: ANOVA, significant differences are indicated by*.