Table 1 Kruskal Wallis tests identify 14 metabolites with concentrations that vary according to diagnosis.
From: Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours
Metabolite | Mean normalized concentration | Kruskall-Wallis P value | Bonferroni corrected P value | Nemenyi post hoc P values | ||||
|---|---|---|---|---|---|---|---|---|
Medulloblastoma | Ependymoma | Pilocytic astrocytoma | Med vs Epen | Med vs PA | Epen vs PA | |||
Ascorbate | 0.039 | 0.018 | 0.022 | 3.2 × 10−5 | 8.0 × 10−4 | 4.0 × 10−4 | 2.0 × 10−3 | N.S |
Aspartate | 0.0076 | 0.0014 | 0.0009 | 2.8 × 10−5 | 7.0 × 10−4 | 8.6 × 10−3 | 1.0 × 10−4 | N.S |
Glucose | 0.002 | 0.014 | 0.019 | 2.5 × 10−4 | 6.2 × 10−3 | 1.3 × 10−2 | 1.1 × 10−3 | N.S |
Glutamine | 0.093 | 0.14 | 0.26 | 1.4 × 10−9 | 3.5 × 10−8 | N.S | 1.4 × 10−9 | 4.2 × 10−3 |
GPC | 0.014 | 0.031 | 0.036 | 2.2 × 10−5 | 5.5 × 10−4 | N.S | 2.6 × 10−5 | N.S |
Glutathione | 0.026 | 0.041 | 0.023 | 1.0 × 10−4 | 2.5 × 10−3 | N.S | 3.6 × 10−2 | 1.1 × 10−4 |
Hypotaurine | 0.022 | 0.017 | 0.045 | 1.3 × 10−4 | 3.2 × 10−3 | N.S | 2.2 × 10−2 | 1.7 × 10−4 |
Leucine | 0.0082 | 0.0014 | 0.0096 | 1.7 × 10−4 | 4.2 × 10−3 | 1.7 × 10−4 | N.S | 3.7 × 10−2 |
Myo inositol | 0.12 | 0.28 | 0.13 | 2.0 × 10−7 | 5.0 × 10−6 | 6.5 × 10−7 | N.S | 4.1 × 10−5 |
NAA | 0.013 | 0.0036 | 0.025 | 3.5 × 10−7 | 8.8 × 10−6 | 4.2 × 10−3 | 1.9 × 10−2 | 3.5 × 10−7 |
PCh | 0.12 | 0.03 | 0.03 | 1.3 × 10−10 | 3.3 × 10−9 | 2.5 × 10−6 | 1.6 × 10−8 | N.S |
Scyllo inositol | 0.0019 | 0.0072 | 0.008 | 1.2 × 10−5 | 3.0 × 10−4 | 2.3 × 10−4 | 8.0 × 10−4 | N.S |
Succinate | 0.0024 | 0.0049 | 0.0099 | 7.7 × 10−5 | 1.9 × 10−3 | N.S | 7.9 × 10−5 | N.S |
Taurine | 0.17 | 0.088 | 0.037 | 6.6 × 10−11 | 1.7 × 10−9 | 8.9 × 10−3 | 8.1 × 10−11 | 1.4 × 10−2 |
