Figure 2
From: MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity
Electroretinogram (ERG) analyses of Mll1KO mice and littermate controls. Whole animal dark-adapted (A–C) and light-adapted (D,E) flash ERGs were performed on 1MO mice. (A,D) Example waveforms in response to the brightest light flash intensity tested. (B,C,E) Mean dark-adapted A and B and light-adapted B wave amplitudes were graphed vs. stimulus light intensity. Error bars represent SEM; *p < 0.05 relative to CreNeg controls by two-way repeated measures ANOVA and Tukey’s multiple comparisons (n ≥ 4). (F) Dark-adapted Mll1KO A and B wave amplitudes for the five brightest flash intensities tested were normalized to the respective mean CreNeg amplitudes and graphed.
