Figure 3

H&E staining of CreNeg (A) and Mll1KO (B) retinal cross-sections at P24. (C–E) Morphometric quantification of retinal layer thickness at the indicated positions from the optic nerve head (ONH). SUP and INF indicate measurements taken 100um from the superior or inferior edge of the retina. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001, based on two-way ANOVA with repeated measures and Sidak’s multiple comparisons test (n = 4). Histologic results at other ages are shown in Supplementary Fig. S1. Cell death in developing retinas assessed by immunostaining for Cleaved Caspase 3 is shown in Supplementary Fig. S2.