Table 1 Main demographic and clinical features of the study population.
Subjects with non IgE-mediated CMA | ||||||
|---|---|---|---|---|---|---|
At diagnosis | Treated with EHCF | Treated with EHCF + LGG | Healthy subjects | |||
Group 1 | Group 2 | Group 3 | Group 4 | |||
N. | 23 | 9 | 14 | 23 | ||
Male, n (%) | 12 (52.2) | 6 (66.7) | 8 (57.1) | 9 (39.1) | ||
Age at enrolment, months (SD) | 11.4 (7.2) | 11.3 (1) | 14.1 (5.8) | 12.9 (7.4) | ||
Age at diagnosis, months (SD) | 11.4 (7.2) | 5.3 (1) | 8.1 (5.8) | — | ||
Vaginal delivery, n (%) | 11 (47.8) | 6 (66.7) | 5 (35.7) | 10 (43.5) | ||
Birth weight, kg (SD) | 3.1 (0.3) | 2.9 (0.5) | 2.9 (0.5) | 3.1 (0.4) | ||
Breastfeeding for at least 1 month, n (%) | 19 (82.6) | 8 (88.9) | 9 (64.3) | 14 (60.4) | ||
Duration of breastfeeding, months (SD) | 4.1 (2.7) | 2.12 (2.03) | 4.55 (4.1) | 3.1 (2.05) | ||
Age at weaning, month (SD) | 5 (0.8) | 4.9 (0.8) | 4.9 (1.2) | 4.7 (1) | ||
p-value | ||||||
Group 1 vs | Group 2 vs | Group 3 vs | ||||
Group 2 | Group 3 | Group 4 | Group 3 | Group 4 | Group 4 | |
Male, n (%) | 0.694 | 0.769 | 0.375 | 1.000 | 0.243 | 0.286 |
Age at enrolment, months (SD) | 0.967 | 0.255 | 0.483 | 0.179 | 0.521 | 0.634 |
Age at diagnosis, months (SD) | 0.018 | 0.149 | — | 0.179 | — | — |
Vaginal delivery, n (%) | 0.444 | 0.471 | 0.767 | 0.214 | 0.433 | 0.641 |
Birth weight, kg (SD) | 0.171 | 0.095 | 0.937 | 0.942 | 0.201 | 0.114 |
Breastfeeding for at least 1 month, n (%) | 1.000 | 0.255 | 0.102 | 0.340 | 0.210 | 0.835 |
Duration of breastfeeding, months (SD) | 0.079 | 0.733 | 0.246 | 0.150 | 0.309 | 0.260 |
Age at weaning, month (SD) | 0.724 | 0.661 | 0.323 | 0.944 | 0.681 | 0.741 |
Familial allergy risk, n (%) | 1.000 | 1.000 | 0.522 | 1.000 | 0.685 | 0.713 |
