Table 3 Multivariate survival analysis.
Characteristic | Localized | Metastatic/Unresectable | ||||
|---|---|---|---|---|---|---|
Relapse-free survival | Overall survival | Overall survival | ||||
HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | |
Age at diagnosis (>65 vs ≤65 years) | — | — | 1.64 (1.19 to 2.26) | 0.0026 | 1.40 (1.02 to 1.92) | 0.0379 |
Tumor grade (3 vs 1–2) | 2.78 (2.08 to 3.70) | <0.0001 | 3.38 (2.36 to 4.85) | <0.0001 | — | — |
Tumor size (>5 cm vs ≤5 cm) | 1.56 (1.13 to 2.15) | 0.0070 | 1.48 (1.01 to 2.16) | 0.0419 | — | — |
Surgical margins (R1 vs R0) | 1.36 (1.05 to 1.75) | 0.0200 | — | — | — | — |
NLR at diagnosis (>2.5 vs ≤2.5) | 1.41 (1.08 to 1.85) | 0.0125 | 1.53 (1.10 to 2.13) | 0.0112 | 1.82 (1.16 to 2.85) | 0.0087 |
LMR at diagnosis (≤2.4 vs >2.4) | — | — | — | — | 1.71 (1.21 to 2.43) | 0.0026 |
Palliative chemotherapy (Yes vs No) | — | — | — | — | 0.62 (0.46 to 0.85) | 0.0027 |
