Table 2 Time-dependent Cox proportional hazard model analysis for non-proliferative diabetic retinopathy associated with juvenile-onset T1DM.
Variable | Multivariable model | Reduced model | ||||
---|---|---|---|---|---|---|
B | HR (95% CI) | P value | B | HR (95% CI) | P value | |
Male | −0.921 | 0.40 (0.19, 0.85) | 0.016 | −0.672 | 0.51 (0.26, 0.99) | 0.047 |
Onset of T1DM at age 5–14 yrs | 1.852 | 6.38 (2.41, 16.87) | <0.001 | 1.701 | 5.48 (2.25, 13.38) | <0.001 |
Duration of T1DM (yr)a | 0.451 | 1.57 (1.41, 1.75) | <0.001 | 0.439 | 1.55 (1.40, 1.72) | <0.001 |
Body mass index (kg/m2) | −0.049 | 0.95 (0.85, 1.07) | 0.402 | |||
HbA1c level (%)a | 0.445 | 1.56 (1.35, 1.80) | <0.001 | 0.454 | 1.58 (1.39, 1.79) | <0.001 |
Annual mean of lab results | ||||||
LDL cholesterol (mg/dl)b | 0.007 | 1.01 (1.00, 1.02) | 0.139 | |||
Triglycerides (mg/dl)b | 0.010 | 1.01 (0.98, 1.04) | 0.527 | |||
HDL cholesterol (mg/dl)b | −0.010 | 0.99 (0.97, 1.01) | 0.349 | |||
Serum creatinine (mg/dl)b | 0.851 | 2.34 (0.78, 7.02) | 0.129 |