Figure 5 | Scientific Reports

Figure 5

From: Immunoproteomic Identification and Characterization of Leishmania Membrane Proteins as Non-Invasive Diagnostic Candidates for Clinical Visceral Leishmaniasis

Figure 5

(A) Reactivity of three electroeluted antigens GP63, α-tubulin and EF1-α along with crude antigens, LAg, were tested against urine samples of kala-azar infected individuals (VL, n = 20), non-endemic healthy controls (NEHC, n = 10), endemic healthy controls (EHC, n = 10), and other diseases (OD, n = 10) including two of each malaria, viral fever, tuberculosis, typhoid, and pneumonia. (B) The whole protein sequence of glycoprotein 63, α-tubulin and elongation factor 1α with their mapped epitopes (red block). (C) In comparison to crude membrane antigens, LAg, reactivity of three synthetic peptides P1, P2 and P3 were tested against urine samples of kala-azar infected individuals (VL, n = 40), non-endemic healthy controls (NEHC, n = 20), endemic healthy controls (EHC, n = 10) and other diseases (OD, n = 18) including 6 malaria, 4 viral fever, 4 tuberculosis, 2 typhoid and 2 pneumonia urine samples.

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