Table 2 Body weight gain, tumor weight and expression of atrophy markers in the gastrocnemius of mice receiving a sham injection and receiving the vehicle in their drinking bottle (CT), mice transplanted with C26 cells and receiving the vehicle in their drinking bottle (C26) and mice transplanted with C26 cells and receiving Klebsiella oxytoca in their drinking bottle (C26-Kox).

From: Klebsiella oxytoca expands in cancer cachexia and acts as a gut pathobiont contributing to intestinal dysfunction

Weights (g)

CT

C26

C26-Kox

Body weight gain

1.26 ± 0.36

−2.21 ± 0.28***

−2.21 ± 0.33***

Weight of the tumor

0.28 ± 0.02

0.25 ± 0.02

mRNA levels

CT

C26

C26-Kox

Fbxo32

1.00 ± 0.10

18.35 ± 2.20***

16.31 ± 2.59***

Trim63

1.00 ± 0.07

17.80 ± 2.56***

15.58 ± 2.82***

Ctsl

1.00 ± 0.04

3.76 ± 0.74*

3.36 ± 0.82*

Map1lc3a

1.00 ± 0.03

2.39 ± 0.17***

2.22 ± 0.26***

  1. Data are presented as mean ± SEM. *p < 0.05; ***p < 0.001.