Table 1 Univariate and Multivariate analysis of the correlation between clinicopathological parameters and overall survival of patients with GC.

From: Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor

 

N = 153

OS

Univariate

Multivariate

P value (Chi square)

Adjusted P value

HR(95%CI)

Gender

Male

99

0.017

0.169

 

Female

54

   

Gene expression

High (≥4281.84)

77

0.037

0.021*

1.641(1.079–2.496)

Low (<4281.84)

76

   

T stage

T1-T2

24

0.000

0.164

 

T3-T4

127

   

Not reported

2

   

N stage

N0-N1

69

0.000

0.815

 

N2-N3

82

   

Not reported

2

   

M stage

M0

122

0.000

0.765

 

M1

30

   

Not reported

1

   

Stage (AJCC7)

Stage1&Stage 2

44

0.000

0.001*

0.264(0.119–0.588)

Stage 3&Stage 4

108

   

Not reported

1

   

Histo Grade

Well& Mod differentiated

54

0.367

  

Poorly& Undifferentiated

99

   

Lauren

Diffuse

62

0.469

  

Non-diffuse

91

   
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