Figure 5 | Scientific Reports

Figure 5

From: Polymeric nanocapsules embedded with ultra-small silver nanoclusters for synergistic pharmacology and improved oral delivery of Docetaxel

Figure 5

(a) UV-absorbance spectra of NCs, Ag-NCPs and DTX-Ag-NCPs showing no plasmonic response with NCs and Ag-NCPs whereas, slight deviation and appearance of curve in case of DTX-Ag-NCPs (b) In vitro drug release studies showing cumulative percentage drug release from DTX-Ag-NCPs and DTX suspension in 2 M phosphate buffer at 37 °C against time over period of 24 h and (c) Oral bioavailability study of DTX suspension and DTX-Ag-NCPs in rabbit (n = 5) showing the plasma drug concentration after oral administration of 10 mg/kg of formulations and blood withdrawn at predefined time interval was analyzed through HPLC. Error bar represents Mean ± S.D. of three experiments.

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