Figure 2 | Scientific Reports

Figure 2

From: Interaction of septin 7 and DOCK8 in equine lymphocytes reveals novel insights into signaling pathways associated with autoimmunity

Figure 2

Characterization of DOCK8 expression in horse lymphocytes. (A–C) Representative DOCK8 expression in different lymphocyte subsets. Flow cytometry analyses demonstrate that DOCK8 is expressed in CD4+ T cells, CD8+ T cells and in B cells (white histograms) with high intensity. White histograms represent specific stainings, grey histograms represent respective isotype controls. Y-axis show the amount of cells included in measurement; x-axis show the intensity of DOCK8 staining. (D) Statistical analyses of geo mean fluorescence intensity of DOCK8 expression in lymphocyte subsets of 12 healthy controls. While there was no difference between DOCK8 expression intensity in CD4+ T cells (white column) and CD8+ T cells (light grey column), DOCK8 was significantly higher (*p ≤ 0.05) expressed in B cells (dark grey column) compared to T cells.

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