Table 1 Interacting proteins of septin 7 in PBL of healthy controls.

From: Interaction of septin 7 and DOCK8 in equine lymphocytes reveals novel insights into signaling pathways associated with autoimmunity

Protein name

Gene name

Accession

Enrichment factor

Actin related protein 2/3 complex, subunit 2, 34 kDa

ARPC2

ENSECAP00000009522

3464,2

Histone H2A

LOC100053378

ENSECAP00000001117

101,3

Cell division cycle 42

CDC42

ENSECAP00000003324

76,6

Capping protein (actin filament) muscle Z-line, alpha 1

CAPZA1

ENSECAP00000014750

71,3

Myosin, light chain 6, alkali, smooth muscle and non-muscle

MYL6

ENSECAP00000016002

69,2

Actin, cytoplasmic 2

ACTB

ENSECAP00000016124

51,8

Septin 6

SEP6

ENSECAP00000021088

48,5

Histone cluster 1, H2bj

HIST1H2BJ

ENSECAP00000001004

46,8

Vimentin

VIM

ENSECAP00000004638

41,4

Fibrinogen alpha chain

FGA

ENSECAP00000008007

40,8

C-reactive protein, pentraxin-related

CRP

ENSECAP00000022415

40,7

Actinin, alpha 1

ACTN1

ENSECAP00000017987

40,3

Septin 7

SEP7

ENSECAP00000020433

36,0

Dedicator of cytokinesis 8

DOCK8

ENSECAP00000010583

32,2

Myosin IG

MYO1G

ENSECAP00000016084

28,2

Flotillin 2

FLOT2

ENSECAP00000010141

23,5

Protein S100-A8

S100A8

ENSECAP00000007199

22,7

Tropomodulin 3 (ubiquitous)

TMOD3

ENSECAP00000018986

20,8

Cathepsin G

CTSG

ENSECAP00000003203

20,4

Septin 2

SEP2

ENSECAP00000015383

18,8

  1. List of septin 7 interactors with enrichment factor ≥18 detected by co-immunoprecipitation and identified by LC-MS/MS mass spectrometry. Column 1 (Protein name) shows name of protein. Column 2 (Gene name) shows gene name of identified protein. Column 3 (Accession) shows matching protein accession number, as listed in Ensembl Horse protein database (http://www.ensembl.org/Equus_caballus/Info/Index). Column 4 (Enrichment factor) shows the ratio of normalized protein abundance from enrichment compared to respective isotype controls.
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