Figure 1

Multi-variate analysis confirmed GA-specificity of the plasma proteome response to ventilation. Multi-variate analysis of SWATH-MS data included (A) principle component analysis (PCA) and (B) partial least squares discriminant analysis (PLS-DA). Venn diagrams depicting the number of proteins expressing increased (C) or decreased (D) differential expression in response to ventilation as determined by paired t-test, p < 0.05. N = 7–8/group.