Figure 5 | Scientific Reports

Figure 5

From: Plasma proteomics reveals gestational age-specific responses to mechanical ventilation and identifies the mechanistic pathways that initiate preterm lung injury

Figure 5

Unique protein-function associations were identified within each GA-group. CIM map representation of significant associations between changes in protein level measured prior to ventilation and at 60 minutes ventilation and functional outcomes in extremely preterm (A), preterm (B) or term (C) lambs. Red squares represent positive Pearson correlations (r ≥ 0.7) and blue squares represent negative Pearson correlations (r ≤ −0.7), with color intensity indicative of strength of correlation. Significance of correlations was calculated using a Mantel test with 1000 permutations. Non-significant results with r values of −0.69 to 0.69 are show in in grey. Functional outcomes have been grouped according to the colour key displayed. N = 7–8/group.

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