Figure 7 | Scientific Reports

Figure 7

From: Potential role of the HOXD8 transcription factor in cisplatin resistance and tumour metastasis in advanced epithelial ovarian cancer

Figure 7

Overexpression of HOXD8 enhancing the cisplatin-resistance in ovarian cancer. After infecting with lentivirus mediated HOXD8 or control vectors (NC group), the ovarian cancer OVCAR-3 and HO-8910 cells were observed by optical microscope and fluorescence microscopic with a magnification of 400 (A,B). Expression of HOXD8 mRNA and protein were significantly up-regulated in OVCAR-3-OV cell (C) and HO-8910-OV cells (D). Cellular proliferation of OVCAR-3-NC and OVCAR-3-OV, HO-8910-NC and HO-8910-OV were detected by MTT assay (E,F).

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