Figure 4 | Scientific Reports

Figure 4

From: Alteration of β-Adrenoceptor Signaling in Left Ventricle of Acute Phase Takotsubo Syndrome: a Human Study

Figure 4

Localization of G protein-coupled receptor kinase 2 (GRK2), β-arrestin2, and 8-hydroxy-2′deoxyguanosine (8-OHdG) in two patients with takotsubo syndrome who underwent endomyocardial biopsy in both the acute and recovery phases. Micrographs showing immunofluorescence stainings of GRK2 and β-arrestin2, and immunohistochemical staining of 8-OHdG in the acute and recovery phases. Arrowheads (yellow) indicate positive signals for GRK2 and β-arrestin2 on the cell membrane, and Arrowheads (red) indicate 8-OHdG-positive nuclei.

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